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J Pathol, , Rev Assoc Med Bras, 47 3 : , Actinic cheilitis: clinical and histological features. J Oral Maxillofac Surg, 66 3 , Early diagnosis and prevention of oral cancer and precancer: report of symposium. Adv Dent Res, 9 2 , Oral cancer- results of treatment in the Copenhagen University Hospital. Acta Otolaryngol Suppl, , COLE, P. JADA, , Exfoliative cytology in evaluating oral lesions. J dent Res, 42 1 : , Squamous cell carcinoma of the oral cavity and oropharynx in young adults.
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Edited by Leon Barnes, John W. Eveson, Peter Reichart, David Sidransky. ENDL, E. The Ki protein: fascinating forms and an unknown function. Exp Cell Res, 2 : , Advances in the diagnosis of oral premalignant and malignant lesions. J Can Dent Assoc, , Defining the risk of oral premalignant lesions. Oral Oncol, , Clinical presentation of patients with oral squamous cell carcinoma when first seen by dentists or physicians in a teaching hospital in Brazil. Clin Oral Investig, 7 1 , Br J Biomed Sci, 61 3 , Globocan Cancer incidence, mortality and prevalence worldwide, Acesso em: 15 de setembro de Risk factors for oral and pharyngeal cancer in never smokers.
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Acesso em: 13 de setembro de The oral brush biopsy: Separating fact from fiction. Efficacy of the brush biopsy. J Oral Maxillofac Surg, , GALE et al. Epithelial precursor lesions - Tumours of the Oral Cavity and Oropharynx. GAO, W. Production of a mouse monoclonal antibody reactive with a nuclear antigen associated with cell proliferation. Int J Cancer, 31 1 : , Suprabasal expression of ki antigen as a marker for the presence and severity of oral epithelial dysplasia.
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J Oral Pathol Med, 33 1 , Acesso em: 06 ago. Medicina Oral. Rio de Janeiro: Guanabara Koogan, Squamous cell carcinoma - Tumours of the Oral Cavity and Oropharynx. Oral cytology: indications, contraindications, and technique. General Dentistry, , The effects of age on survival and other parameters in squamous cell carcinoma of the oral cavity, pharynx and larynx.
Clin Otolaryngol, 23 1 : , Oral cancer: prevention and detection. Med Princ Pract, 11 Suppl , Oral Cancer.
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Abul K. Abbas
J Tenn Dental Assoc, 81 1 , KATZ, H. A critical evaluation of epithelial dysplasia in oral mucosal lesions using the Smith-Pindborg method of standardization. J Oral Pathol, 14 6 : , The use of exfoliative cytology for the early diagnosis of oral cancers: is there a role for it in education and private practice? J Cancer Educ, 13 2 : , Factors related to delay in diagnosis of oral squamous cell carcinoma in southern Thailand.
Oral Oncol, 37 2 : , Ror2 expression in squamous cell carcinoma and epithelial dysplasia of the oral cavity. KOSS, L. New York: Lippincott Willians and Wilkins, KOTT, I. The importance of margins in surgery. J Surg Oncol, , The Proliferatingspecific human ki protein is a constituent of compact chromatin.
Exp Cell Res, 1 : , In reply to: When is an oral leukoplakia malignant. Evaluation of a new binary system of grading oral epithelial dysplasia for prediction of malignant transformation. Oral Oncol, 42 10 : , Why oral histopathology suffers inter-observer variability on grading oral epithelial dysplasia: An attempt to understand the sources of variation. Oral Oncol, 43 3 : , Acetaldehyde production from ethanol by oral streptococci.
Oral Oncol, 43 2 , Pathological study of epithelial dysplasia on surgical margin in squamous cell carcinoma of the tongue. J Jpn Soc Oral Tumors, 14 3 : , Immunohistochemical study of syndecan-1 down-regulation and the expression of p53 protein or Ki antigen in oral leukoplakia with or without epithelial dysplasia.
J Oral Pathol Med, , Evaluation of epithelial dysplasia on surgical margin in squamous cell carcinoma of the tongue with stage I,II. Japanese Journal of Head and Neck Cancer, 32 4 : , A study of effects of mouthwash on the human oral mucosa: With special references to sites, sex differences and smoking.
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The use of an oral brush biopsy without computer-assisted analysis in the evaluation of oral lesions: a study of 94 patients. Baseado na celularidade retida em instrumentos de coleta. Disparities in risk of and survival from oropharyngeal squamous cell carcinoma. Clinical implications of continued alcohol consumption after diagnosis of upper aerodigestive tract cancer. White Dental Mfg. Extensive oral mucosal ulcerations caused by misuse of a commercial mouthwash.
Cutis, 64 2 : , A study of exfoliative cytology of normal human oral mucosa. J D Res, , fev. Med Oral, 7: , Pesqui Odontol Bras Acesso em: 10 jun. Identification of a recurrent oral squamous cell carcinoma by brush cytology. Diagnostic delay of oral squamous cell carcinoma in two diagnosis centers in Cordoba Argentina. Natural history of potentially malignant oral lesions and Conditions: an overview of the literature. In this context, taste alterations are frequently reported by crack cocaine addicts .
Howe- Statistical analysis ver, in literature, clinical researches on the effects of crack cocaine use are scarce. Thus, this study investigated whe- All the data were tabulated and statistical tests were ther the chronic use of crack cocaine is able to alter the performed with SPSS for Windows IL, USA. These results were analyzed for normal distribu- tion using Shapiro—Wilk's test.
The Mann—Whitney test was used to assess whether there was statistical differences in Materials and methods taste perception between groups.
The mean age of the experimental and control group was of Subjects 31 years 21— These individuals were using Thirty crack cocaine addicts case group and 30 healthy this illicit drug for more than seven years. Name, patients concomitantly used crack cocaine and cocaine age, sex, occupation, and relevant medical history were 3.
Furthermore, marijuana use was reported by recorded. Concerning alcohol con- media, anemia, and hepatitis were excluded in this study. Regarding sour taste, the groups had similar respon- ses. All patients in case group and 23 Tongue depapiled 2 6.
The value for the 10th percentile was four Fordyce spots 1 3. Then, 20 Use of medications before hospitalization Yes 11 Recently, it has spread across Amphetamines 1 3. One of these changes is the loss of taste that has been reported by many of the drug addicts . To date, there is no report in the perceived by both groups.
Thus, the purpose of this study was to evaluate concentrations tested. They often confuse them with the the gustatory function in crack cocaine addicts. In general, these individuals did not recognize the users, especially for sweet, bitter and salty. Although these mechanisms responsible for adverse effects of drugs related groups had a similarity in the responses, the control group to the taste disorders are poorly understood.
In many cases, had a greater number of correct responses in 10 of 12 they are probably multiple and interactive. Thus, the drug- solutions offered. This creates a problem in terms of an appropriate candidiasis , 4 Neuronal impulse propagation changes for assessment.
However, direct observed in this study.
Many crack cocaine addicts interpreted differently. A study by Landis and colleagues  live or lived in the streets and, in this condition; they do not using the methodology of the paper strips hypogeusia repor- realize their personal hygiene .
Poor oral hygiene can lead or two cases per individuals. In impact on nutritional status and quality of life of these general, thermal agents contribute to modify the oral structu- individuals [30—32]. The smoke comes into contact with the oral mucosa and leads to the formation of a layer of keratin in non-keratinized or an increased keratinization of the oral Conclusions epithelium similar to what occurs with tobacco smoking .
This increase in oral keratinization is called hyperkeratosis. Also, some taste. Another change frequently observed in epithelial tra- cheobronchial mucosa of crack users is metaplasia [20, 21]. None declared. The damage to the The work described in this article has been carried out in gustatory function in smokers was also reported in by accordance with The Code of Ethics of the World Medical Vennemann and colleagues , but only in individuals who Association Declaration of Helsinki for experiments invol- used 20 or more cigarettes a day.
Cad Saude Publica ;24 Suppl.
7 CONCLUSÕES - Universidade Federal Fluminense
Head Neck Pathol ;2 3 — Robbins pathologic basis of Constantinidis J. Effects of smoking on taste: assessment disease, 6th ed.
Philadelphia: W. Saunders Company; with contact endoscopy and taste strips. Laryngoscope Med J Aust ;— J Natl Cancer Inst ;90 16 : smoked cocaine self-administration in humans. Neuropsychopharmacology ;31 4 — Tracheobronchial histopathology in habitual et al. Chest process: report of three cases including treatment. Oral ; 2 — Bogliolo Patologia Geral. Identifying oral lesions associated with crack cocaine Janeiro: Guanabara Koogan; Camila Maciel.
Markman DeVita. Ausiello Goldman. Knight Shetty et al. J Oral Pathol Med, 35 6 : , Mortele Osborn. Madoff Debois Kerr et al. Fernandes Lippert Barros Filhos. Silva Filho Hammer. Effects of contusion and cryotherapy on microvascular perfusion in rat dorsal skeletal muscle.
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